b-gata h-kei
A 4koma by Sanri Youko, published from 2004-2011 in Weekly Young Jump and adapted into an anime in 2010. The anime's English release was retitled "Yamada's First Time."
Yamada is a sex-crazed virgin who hopes to have 100 sex friends by the time she graduates high school. Unfortunately, her attempts to kindle sexy times always fall short.